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Ivermectin as a Prophylaxis
Prophylaxis intervenes in the first phases of COVID-19 infection, which is mainly asymptomatic, when the virus replicates to increase its viral load—symptom onset occurs after the viral load peaks.

Ivermectin can be effective in the early stages of infection. Outside the cells, ivermectin can attach to parts of the virus, immobilizing it and preventing it from entering and infecting human cells.

Ivermectin can also enter the cell to prevent the virus from replicating. SARS-CoV-2 needs cell replication machinery to make more of the virus; ivermectin attaches and blocks a protein critical to this process, preventing viral production.

Additionally, ivermectin can be absorbed from the skin and stored in fat cells for a long time.

“Because it’s lipid soluble, it is stored and slowly released, once you’ve taken a prophylactic dose, and I think it’s like the cumulative dose of about 400mg, that your risk of getting COVID is close to zero and you can actually stop it for a while,” said Dr. Paul Marik, a widely published critical care specialist with 500 peer-reviewed papers to his name.

' Ivermectin for Early and Acute COVID
Many peer-reviewed studies have found that ivermectin, when used by itself or in conjunction with other therapies in symptomatic patients, reduces ventilation time, time for recovery, and the risk of progressing to severe disease.

This is likely due to ivermectin’s anti-inflammatory role in multiple pathways, achieved by clearing out the viral particles by immobilizing them, reducing inflammation, and improving mitochondrial action.'