I've been in that situation for quite a few years now.
I seek out friendship from a variety of people.

First, directly ask them why their attitude toward you has changed. You may have said or done something that offended them, and until you know why you won’t be able to make amends. Offer in advance to apologize for whatever it was. If their reason is something that is for you a non-negotiable, such as having to adopt their religion, then be clear with them that while you respect their wishes, you cannot do what they want. Second, you may have to accept that you won’t be given a “why,” and no-one has an obligation to care for you. In the end, that obligation is always yours.

You rely on yourself. You begin to view life and society in a new way. Those who become friends become the equivalent of family. You smile with your ability to function alone, and you keep digging..

My initial feeling is of empathy but I would need to know more about the situation for a suitable response .

There is always a reason...