edit- Great answers! Many have the obvious reason of being a startling noise or a noise that irritates. I'm wondering about sounds that creep you out without explaination.We know music can make us feel. What is interesting to me is that certain sounds can cause discomforts like fright or anxiety without having a known reason (such as PTSD or other negative memory). Children often deal with this. The sound of a train horn, or a noise in the wind. What sound naturally makes you uncomfortable?
Yeah, Church bells on a Sunday morning. Especially when I've had a few beers/scotches on a Saturday night and that is every Saturday night.
Not really a sound but I say something and the person ask me questions about what I said, mainly in a challenging tone.
The orange one's voice.
The screech of vehicle brakes , with a following metal crash ...
Noisy, smacking chewing.
Hearing the dentist's drill, while waiting my turn !
A baby crying - or worse - screaming.
On TV , or in a movie, amplified gulping sounds.
Here is a strange one: dripping faucet.