[snopes.com]

[en.wikipedia.org]

Parts of this video set off my Bullshit Detector, it was too choppy and convoluted in presenting a reasonable argument. What it amounted to was casting aspersions on the CDC, Dr. Fauci, Bill Gates and the WHO, suggestions of corruption, greed and criminal acts are not the same thing as producing a smoking gun. From the way the video clips were pieced together I would be willing to go out on a limb and say that at least in part her statements were taken out of context.
What is more disturbing to me is that we live in an age where we no longer trust the fifth estate to provide us with reliable information and the same goes for our government institutions, many people no longer trust them. I have been disgusted to hear politicians offer to level with their citizenry as though they were doing us a favour by proposing to tell us the straight goods, as if we were children that can't handle the facts so they just feed us convenient lies all the time, except on special occasions like pandemics.
A few things of note:
She doesn't say that the virus was genetically engineered but that the virus had been accelerated in its evolution. Gene splicing would leave obvious markers that any decent geneticist would be able to spot but accelerated evolution which is selective breeding would look perfectly natural because this is the way that viruses evolve in the real world.
She also implicates Dr. Fauci in the horrible response to the AIDS pandemic and the millions of lives lost as a result. Certainly the response was lack lustre at best and the virus was touted as a cure for homosexuality, intravenous drug users and others that were deemed unfit for society by some right wing types. No smoking gun but definitely a case could be made that the public health organizations dragged their heals when it came to finding a cure and fortunes were made by the makers of the miracle drugs.
The absolute bungle that has been the response so far in the USA, UK and other nations does lend credence to the idea that perhaps there is an underlying agenda at work and I doubt this video would have gained any traction otherwise. The POTUS rambles on incoherently at daily briefings to the point that many journalist don't even bother to attend these sessions or refuse to air them live because of the inaccuracies presented. The actual numbers are not nearly as high as one would expect in order to justify the lock down of the world and the collapse of the global economy, I don't know a single person who has died from COVID but I do know some people who will lose their businesses, their homes and their life savings before the summer is out. It is little wonder that people are having doubts about the pandemic but let's see what round two brings us, possibly much more devastating than round one but time will tell.
The final teary segment right at the end of the video was designed to tug at the heart strings and that's not good journalism, that's spin and it made me question everything in the video even more. It incites panic, distrust and fear at a time when people are already under a massive amount of stress and are therefore less likely to consider things coolly and logically.
I think something may be rotten in Denmark but I don't think this is it, maybe it will help us track down what is actually causing the smell.

And here's another:

[cnn.com]

Here's one that offers quick (not detailed) rebuttals to several claims:

[digitaltrends.com]conspiracy-theories-and-myths

I'm afraid that I don't understand virology well enough to help on that front.

If it were me, though, I would approach this from a different direction anyway: statistics, politics, and logic. Such a conspiracy, after all, would necessarily involve a great many players who aren't generally known to work well together.

I'll see what I can dig up.

Meh, I'm not going to do your OR their research for you. Google is your friend. Ignore hits from sources that aren't credible / reputable.

If they are conspiracy theorists then you'd be wasting your time anyway.