The adenovirus vector vaccine may have more long term efficacy. UK AstraZeneca real world data from 100 million vaccines worldwide.

@Kbdank71 If you think we will probably never get herd immunity then you are not paying attention to the science. It's not like the Flue. There are over 200 influenza virus types and they have had 1000's of years to evolve and mutate. And the more they mutate the less deadly they are. The annual Flue Vaccine is based on what Flues are likely to hit in any particular Winter. Usually based on what flue outbreaks are in the southern Hemisphere (Australia, New Zealand and south east Asia) 6 months earlier. All Covid Virus's do not mutate as rapidly as the influenza Virus does (that includes the common cold Covid Virus thats been around for 1000's of years or more). But you may have a point about herd immunity being difficult to achieve in the US with so many Trumpers saying they won't take it. As for the rest of the world that may not be as big a problem to overcome. In my Country Ireland we have not politicised the virus and we have 30% of people that are Vaccine hesitant. But that relates to AstraZenica because of Blood Clots. 90% of our Vaccines are Pfizer and Moderna. So we are at over 80% willing to take the Vaccine already and that will get higher as time goes by. And the evidence from countries like the UK and Israel that have advanced vaccine roll outs is that Covid19 starts to disappear very quickly. Once a Vaccine achieves herd immunity then it become really difficult for a virus to mutate. Mutation requires huge number of infected people to be able to achieve mutations that can spread. This is why we don't have Polio in the developed world anymore. Polio did not mutate to dodge the Polio vaccines effectiveness. When it come to mutations that are varied and different from the original virus the Flue seems to be the exception. Most Virus can be controlled by vaccines. Polio, yellow fever, Typhoid, and other are good examples. There may be variations and tweaks done to the Covid Vaccines but they should be effective and should remove covid 19 from our lives completely.

Lets not forget how effective other Vaccines have been and realise that the odds are in favour of Covid 19 vaccines working well and working well in to the future.

@Kbdank71, @barjoe
It a real shame that the UK AstraZeneca pharma company cannot seem to meet its production targets and promises. With every contract they signed being undermined by their own bad performance in producing their own vaccines.

AstraZeneca left Europe 90 Million Vaccine doses short already. An incredibly bad performance by them. However. Pfizer have been an amazing company. They have overproduced vaccine and have supplied an additional 75 million doses for Europe and are meeting all their delivery targets so far. In fact they are surpassing them. Despite a bad start in Europe we are now on track to have 80% of the adult population given their first dose of Vaccine by July of this year. In Ireland 80% of our vaccine supply is now Pfizer, a reliable supply source. With news 3 days ago that Pfizer had another 75 million doses above their contract amounts for Europe, there is a great sense of optimism now in Ireland. We are getting there now. 25% of adults will be vaccinated by the end of next week with 50% of Adults getting their first shot within 5 weeks. And in the last 3 weeks all vaccination targets (Jabs in arms) have been met. I'm optimistic.

@dermot235 Much of the production comes from India for the Oxford vaccine. The need for domestic use in India and UK are hurting distribution. Trump administration wrote AstraZeneca contracts that US couldn't export or resell doses they they agreed to purchase. Is is sitting on and have paid for 50 million doses of a vaccine they haven't used and AstraZeneca hasn't ed applied for emergency use authorization, which probably would be granted eventually.

@barjoe 40 million doses of Astra Zenica were exported to the UK from European Factories in the Netherlands and the UK factories did not reciprocate. India has nothing to do with it. The UK government and AstraZeneca did an disgusting thing to Europe. Pfizer, a more mature company handled things differently. Thats the core of it.