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I've been studying molecules that have been written up as slowing or stopping Alzheimer's Disease (AD). It started with a paper on CBDA, but has led to several other classes of molecules and the influence of diet. Alzheimer's takes people through a real horror story as it robs the victims and their families of their humanity, their dignity, and their savings. Inflammation causes the brain cells to go down metabolic paths that end in cell death, brain scarring, shrinkage and ultimately death. It's slow and miserable.

And yet, despite poorly effective medications, diet appears to be a readily available means to prevent AD. And not only AD, but arthritis and other common conditions. Often, the same herbs or foods contain the molecules that prevent or slow the progression of AD and arthritis. A Chinese paper on herbs described a host of beneficial herbs although half were the usual suspects: ginger, turmeric, saffron, black pepper, etc.

One group, polyphenols, seems very effective, but they suffer from poor bioavailability. They just don't pass from the gut. Some of these are notorious as 'anti-aging' (i.e. Fisetin).

CBD may boost polyphenol effectiveness by inhibiting the liver enzymes that would break them down. Slowing down degradation enables a higher concentration in the bloodstream, or so it seems. CBD receives criticism for this liver enzyme inhibition, but the same thing happens with piperine, the ingredient in black pepper that boosts the efficacy of Tumeric/curcumin.

If you have questions, ask away.

racocn8 9 Oct 23
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The connection between herbs, foods, and their impact on health is an intriguing area of study. Thank you for sharing your insights!

Your research into molecules combating Alzheimer's is truly fascinating! It's heartbreaking to witness the toll AD takes on individuals and their families, stripping away their humanity and dignity. The slow and miserable progression of the disease underscores the urgent need for effective treatments.Have you delved into the benefits of CBD oil 10%? Some studies suggest it may possess neuroprotective properties, making it a promising avenue for further exploration in AD research. It's inspiring to see how interdisciplinary approaches, from molecular biology to nutrition, are shedding light on potential solutions to this devastating disease.

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