I don't know biggest, but people who drive with their high beams on in bumper to bumper traffic on a dark night. I understand I can move my rear view mirror, and fold in my side mirror, but I shouldn't have to. The blinding light is dangerous to drivers it affects, and offers no help to the driver who can clearly see my car just inches in front of them!

I dunno if I’d say this is still the biggest because I don’t often need to shake a lot of hands anymore, but one of the biggest is when a short alpha male shakes my hand (I have to figure this happens to a lot of big guys) they often aggressively squeeze too early on the fingertips so as not to give you a chance to get a real grip on their hand. It makes you feel like you’ve given a ladylike handshake but really they’re just too afraid to let you get a real grip. I just have to shake my head, wipe the fearstain off my hand and keep movin. It’s super repulsive. If it happens again I’m either gonna confront them or curtsy, not sure which.

I don't pet my peeves. They bite.

Dishonesty

Controlling men.

willful ignorance.

Evangelical Christians right wing Assholes

When I want to open my sliding door and windows to let in the fresh spring air and my neighbors are out smoking cigarettes so I get to smell THAT instead. (We wait so long for springtime here in Wisconsin...when it arrives it is appreciated!)

Endless war.

Backpack wearing idiots on crowded mass transit cars..or busses..

Littering.