I read the Dune series some time ago so do not remember nomenclature for the gear worn to recover water for the "natives" of Dune but that is one technology that will probably someday be adopted when other planets are colonized. The most unique technology was the use of "spice" to allow the "transporter" race to bend space to allow delivery of the spice, and other goods, in a timely manner across light years.

An AI implanted in the heads of exiles to aid them in their survival as well as a deterant to returning. Or resonance cannon that reads the resonance of the target and creates a pulse to destroy the target. Both from Veiled Stars available on Amazon.

The nano tech from the Old Man's War series by John Scalzi.
The first three are both excellent sci fi in their own right and a brilliantly executed tribute to many of his forerunners in the genre. He starts in Heinlein and finishes in Dickson.

BOLOs (concieved by Keith Laumer) are 35000 ton contenental seige machines equiped with plasma canons and an AI that allows introspection and gives the BOLO a personality. The BOLO can decide if it will fight or not, it's aware of it's own mortality and in some stories you think it has emotions, not programmed responses.
In one story after a galactic war has mutually destroyed most of the Human and Melconian race, the survivors of each race end up on the same planet. They are at each others throats to kill the last remnants of the others, a BOLO brokers peace between them allowing them to coexist peacefully and continue their species by learning tolerance and cohabitation.

Not so much tech but a planet of truly androgynous sentient beings in “The Left Hand of Darkness” by Ursula K. Le Guin. All individuals biologically experience male and female biology.

Ubik by Philip Dick- a machine that puts a person on the brink of brain death into stasis, allowing the last seconds of their life to be put on pause so that loved ones can continue visiting them. Each time they are partially awoken for a visit they continue to die but at a decelerated rate, and whilst in stasis they can make contact with other people in the same situation in a sort of technological afterlife.

Duuude. Just look to the US govt. Look up the Philadelphia Experiment, Mauntauk Project, Dulce Base, S4. It's real...and the hole goes deep.

Shadow Man by Melissa Scott: the computer interface is non-physical; one operates the computer with the hands, contacting nodes of thermal differences and vibration and whatnot. Kind of like the gestural stuff we have now...

I thought the "Point of view gun", from The Hitchhikers Guide to the Galaxy movie, was truly original:

If you know Issac Arthur's work, then you probably know this one. Mining the Sun for hydrogen and other things, to prevent it from becoming a red giant and vaporizing Earth in about 4 or 5 billion years. It isn't fantasy, it is speculative science, and probably is possible.

Slo-mo on the film Dredd. fucking brilliant film

The SEP device from the hitchikers guide to the galaxy. This device allows you to do the impossible, by making it Somebody Else's Problem that it's not possible. Want to walk on the surface of the sun? No problem, since it is no longer your problem that you should be atomised and dead. In a quirk of probability every time an SEP device was used it would become the same other person's problem. This poor unfortunate then became the most overworked being in the history of the universe.

The TARDIS. I've not seen anything else like it. Sure, there are knockoffs, but nothing similar seems to predate it. There are plenty of things that have time and/or space travel, or are bigger on the inside, but the specific combination of everything that goes into it is so iconic and unique that it pretty stays in Doctor Who.

I'd go for the Protomolecule from the Expanse book series. It's basically a bioengineered extraterrestrial microscopic organism capable of doing feats such as assembling itself into a wormhole portal, breaking the laws of physics, infecting living creatures, surviving the surface of venus and an asteroid impact etc. If you're not familiar with the Expanse series, I'd recommend you read it.