Both parties need to be on the same page for sure. Be clear with your expectations, what you don't like and want/need.

You have not mentioned what efforts were made to remedy their issues with medication. I'm assuming you were fair to them by at least talking about using meds. If they turned that down then I think you did all you should have.

Be careful what you wish for.
I didn't hit my prime until 40. married to young to a starfish.
Next relationship was great while it lasted, the girl believed she must have been a nympho maniac as no guy could keep up with her. It was awesome.
Sadly, ladies my age now say they have other interests, sex is only ocassional at best, they just are not that interested. I know medication is part of the reason for some. I coudl not go into a relationship with someone who was not compatible in this regards. Though if the relationship was good in other ways, I would no doubt stay if things fell apart n bed. I get offers from younger ladies who voice complaints such as yours, but I am age conscious and prefer someone within about 5 years of my age, either way.
I will expand that for a very active older lady, or a very intelligent younger one, but not my much.

Sorry to hear you had those kinds of experiences. I might be on the younger end here so I might not be able to speak for the older guys (I'm 34) but if I'm into someone then sex is never an issue like I can go multiple times in a day for a pretty long period, sorry if that's TMI there. Just saying if it came ro it I would be poping the little blue pill like a pezz dispenser. Sexual compatibility is very important to me as you can see. Wishing you the best and I'm sure there are guys out there your age that can keep up with you and their um yeah you know lol

I have discontinued pursuit of relationships due to sexual incompatibility. I feel comfortable in that because I try to be very open about sex with any partner I have. I want to learn her needs and desires, and also try to be clear about what I enjoy. If we are not compatible, it is not because we did not discuss.
I have also had sex drive become an issue. If one person needs a lot and the other does not want very much, that is hard to work through without swinging or an open relationship.
No matter what issues you have, the key is to communicate and to be honest about whether they are deal breakers. Trying to push through serious issues without addressing them is a recipe for resentment and disaster.

I think you have to have a similar level of interest as your partner. I've been with people who I was much more interested in sexually than they were interested in me. I've also had the opposite. Neither situation is fun for either person.

I have no interest in being a "bride of christ" to a mortal man. You can be BFFs but for a one on one romantic relationship to work there has to be sexual compatability otherwise there is frustration, resentment, one party feeling pressured and things going to shit. If neither of you are interested in sex that's fine but if one is and the other can't come to the party there's a problem, either you ditch the one on one part or you ditch the relationship or change its nature.

Warning as you get older it gets worse, they talk the talk but in many cases they can't walk the walk.

Well, after finally having a partner who matched me sexually..mild S&M, gender role switching, fantasy games, dominating and being dominated, costumes, constant play for hours almost daily, I have zero wish to have cis hetero "rabbit sex"-quick as possible, with orgasm as the goal. SO boring I'd rather be single or live platonically.

But I'd like a dance and hiking partner, and since I'm demisexual I can take sex or leave it.

You are saying "sexual compatibility" but you are describing unsatisfactory (to you) performance. If your partner is unable to satisfy you via intercourse, but is willing and able to do so in other ways, wouldn't that work? Maybe a clearer definition of what you feel compatibility is would be helpful. =]

It's important...honestly i can be physically attracted to a woman but if i don't actually have an emotional connection too i don't perform so it could be more mental than physical but then that would still mean there's a compatibility issue

Got to be compatible

For me, if any romantic relationship has any chance of working, sexual compatibility is vital.
Without it, what the hell is the point? You're just friends.

I think it is important... Emotional and intellectual intimacy are awesome but pure physical attraction is essential for the trifecta.

I think if you truly love eachother you can work around sexual incompatibility. Finding new things, experimenting, figuring it out. Ultimately if you cant, try swinging. That way you both can find what you're wanting, and still keep your relationship strong. I personally don't like the idea of my so sleeping with someone else, but knowing my sexual issues, it wouldn't be entirely off the table, as long as there was a long time of trust and ground rules involved. Being someone who is not the most sexual in nature, I'd prefer finding someone else who has sexual disfunction as well and can get by with maybe twice a month instead of frequently. If, however, we are deeply in love and he just can't get by on once or twice every few weeks, then we will have to sit down and talk about it. I'm mostly up front with my potentials that I am sexually disfunctional and that I am willing to later in the relationship look at ways to get around it.