"These arms of mine" : Otis Reading - too many times!
"Non, rien de rien" : Edith Piaf - Life!

Growing up Bonnie Tyler's " Total Eclipse of the Heart" got me through a lot. But currently "Thunder" by Imagine Dragons speaks my "soul."

As someone who has battled lifelong depression this song hit me really hard.
Just be warned that if you listen to it by yourself it may or may not bring you to tears.

This one is mine. Meant a lot to me as I was going through a divorce at the same time my children were leaving the nest for college

So many but this one sticks out. I was traveling in Israel past the detritus of millenia of conflict, when we passed a sign that said "Armageddon welcomes careful drivers"

Green Hell by the Misfits

After the car accident in '87 that left me disabled with a traumatic brain injury, the song I related to most was: Looking Out From Nowhere by Michael Schenker Group.

"Imagine" by John Lennon

My cars didnt had pet names but they had "sountracks". Sometimes very personalized to them like my trooper "Beds are Burning", my impulse "broken wings", before the accidents was "shout". I don't do that anymore. Music is the Universal Healer.

summer song. chad and jeremy. my first girl friend and this song. yikes that was a great time to be alive

Different songs for different journeys. Sometimes it might be Journey!

I agree with your post, in respect to your question about songs being meaningful on life's journey. I would have to say however, there is just too many to mention right now. I do believe however, that music's greatest strength is it's ability to transcend all barriers.

So many.
No one came / deep purple
Tonight / tv on the radio (check it out if you've never heard it)
Ready or not / Michael hedges
It's alright / Neil schon
With you there to help me / jethro tull
I think it's going to rain/ Randy Newman
Don't let it bring you down/ Neil young
Surrounded or spiraling / silver sun pickups
Shoe salesman / Alice Cooper

....I could go on and on......

A lot of songs, but a few singers -- Simon and Garfunkel, Edith Piaf, Bette Midler, Nina Simone, and a few others.

You are so right. It speaks to you in your thoughts. At the time you are in that place. And is always good for the spirit.