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Has anyone rested successfully on a red eye?

I'm taking my flight to NYC from Seattle on tuedsay night and I'm not a fantastic sleeper to begin with. Anyone have a trick to getting actual sleep? I want to run around town, not be sleepy. I'm usually an early bird so I think that will help with the time difference. I was thinking of taking benadryl; its helped me sleep in the past quite well with no grogginess in the morning.