Monster-in-Law with Jennifer Lopez and Jane Fonda is a good one.

I lean a bit to quirky so some of these are a wee bit on the dark side but off the top of my head:

An Everlasting Piece (about hairpieces in 80s Ireland)
The Taste of Tea
My Cousin Vinny
Seven Psychopaths (with brilliant performances by Sam Rockwell and Christopher Walken)

Oh, and in a nod to the season, Shaun of the Dead.

Amongst my favourite comedy films are Monty Python's Life of Brian and Down and Out in Beverly Hills.

If we're talking films specifically, ever since I was little I've loved Harold Lloyd's silent movies, which still hold their own after a century. More recent choices are Amélie and Les Triplettes de Belleville.

As for TV series, Monty Python's Flying Circus has to be towards the top of the list (though as was pointed out on Family Guy, approximately 90% of it is neither clever nor funny); so too do Look Around You (a brilliant pastiche of 1970s Open University lectures on TV), golden era Simpsons, The Fast Show (which I believe was called Brilliant in the US) and the extremely dark comedies Monkeydust and JAM.

A fish called Wanda.
Kung Fu Hustle.
Mean Girls.
Death Becomes Her.
The Witches of Eastwick.

The Passion of Christ was probably the worst comedy ever made.

"The Jerk", "Blazing Saddles", "Holy Grail", "The Life of Brian", "Sleeper", and "Take the Money and Run"

Hard for me to choose favorite comedies; so many to choose from, but I I like the early Eddie Murphy stuff.

Pineapple Express
Grandma's Boy
Happy Gilmore
Being John Malkovich
Hot Fuzz
Scary Movie
Borat
Super Bad

Blazing Saddles, It's a Mad Mad Mad Mad World, Young Frankenstein, Life of Brian.