As someone whose entire life is being destroyed by a genetic mutation in my DNA, yes

Absolutely! Genetically "cleaning up" human dna to eliminate/filter out hereditary disease and any life-extension modifications. I think there must be endless possibilities.

We have always been genetically modifying our species with mate selection. CRISPR will make it more targeted, which is good, but reality has the tendency to be far better than what I can dream up, so we should allow for it to surprise us rather than only allowing that which we think is best.

We are already directing our own natural selection by other means.

I have no problem with gene editing if it's done very cautiously and with awareness that everything is connected / related and the law of unintended consequences can be particularly nasty in this area.

We should aim for extinction.

This is fraught with ethical problems. Think of the eugenics movement and its associations with Naziism.

The question is not should we, but when will we.

If it can remove genetic disorders, we're morally obligated to do so, I think.

Unfortunately, morals, integrity, empathy and kindness aren't contained in DNA, so why bother?

No one cried when we got rid of polio. If we can do that genetically, why not?

Yes, especially to get rid of diabetes and other genetic diseases. Instead of increasing intelligence, I would increase integrity if it van be genetically isolated.

Guys, are you aware that Dr. Mengele's studies in genetics are very much used / studied by today scientists?

NO.
Once again, this speaks directly to the inevitability of unintended consequences.
Typical human arrogance though.
That's fine. We're just going to unintentionally fuck ourselves right out of existence.
Might as well go ahead and bring back the dinosaurs. We'll fare just as well with them.

As I understand it, it is difficult to make changes in one area without also generating changes in another. Like an infinitely more complicated rubiks cube. So vanity projects like turning yourself into Captain America or Einstein will likely always be out of reach.

However, let's say we solve that particular conundrum and we can get the precise results we want with minimal side effects. The technology and procedures won't be cheap. Outside of specific medical conditions any changes you want to make will be the definition of an elective procedure. Insurance won't cover it. I don't know about you but I can barely afford my share of my regular prescriptions, let alone hundreds of thousands of dollars in out of pocket costs for night vision or any other enhancement. But you know who can? The 1%.

So what will happen is a furthering of the class divide as the wealthy make themselves faster, stronger, smarter, resistant to disease, and longer lived. Each generation improving by leaps in bounds over the previous one. Meanwhile everyone else is stuck in the shallow end of the public gene pool, evolving the old fashioned way.

If you think there's inequality now, just wait until the wealthy are quantitatively better then us in ways that can be tested and measured. Once we start down this road it will be almost impossible to change course.

Yes. We should. But we need to be very careful.

Theoretically this has lots of promise, thinking especially about attempting to eradicate genetic disorders, the problem comes when we look at how this will be controlled and who does the controlling!

If humans don't do it voluntarily then I expect that AI will do it for us. Biological units are very useful but they would benefit in efficiencies if they were enhanced genetically and mechanically. Nanobots have already been used experimentally on human disease so it is only a matter of time before we see breakthroughs in this area.

No. I'm not willing to tempt whatever unknown circumstances for this sort of thing. Nature has a way of balancing out what it needs and I don't want to see the fall out.

100% yes. I can see no moral objections at all,..... only a grey area if you don’t understand how evolution works, believe that god exists & wants us to suffer,.... or you take away peoples right to choose.

Whether I want to combat disease, grow new limbs,..... or even have a kid with blue eyes,..... the answer is yes. .....& quickly please!!

I'd say that it is fine to genetically alter all assholes. Oh by the way, I get to pick who is in that category

We already are. Right now they are very small improvements like the removal of a disease from the genome of an embryo. It will acceleration. In a million years we will control who and what we are. Moral or immoral - it will happen.

Like all things done in the right way it's a great idea but I can see how it could be mis-handled.

Yes, because we have enough genetic corruption and frailty to collapse at least one civilization. This makes every civilization on Earth prone to this problem.

Are we supposed to leave this issue to people who know nothing?

Seems a viable way to get rid of diabetes.